Word: a-beta
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Dates: during 2010-2010
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Goldstein also mentioned the debunking of earlier theories about A-beta as one of the significant contributions of his research...
Moir added that the laboratory was now examining the relationship between A-beta levels in live animals and their susceptibility to infections. The study’s researchers said they believe that their surprising discovery of a new function for A-beta has implications in the search for new treatments for Alzheimer’s disease...
Tanzi and colleagues discovered similarities in function between the Alzheimer’s disease-related protein beta-amyloid, or A-beta, and LL-37, a well-known protein found in the first line of defense in the immune system...
...This finding gives us a strong inkling of what [A-beta] is doing and can provide us with some clues, not only about the origin of the disease, but also how to think about it therapeutically,” said Lee E. Goldstein, one of the study’s co-authors and a professor at the Boston University School of Medicine. “It’s likely that A-beta plays an important protective role in our health, in addition to being what was once considered a ‘bad peptide...
...some cases, researchers found that A-beta was more effective as an anti-microbial protein than LL-37. But Medical School professor and study co-author Robert D. Moir said that researchers need to now focus on making sure the findings on the beneficial function of A-beta apply to actual people...
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