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Like dinitrophenol, Prontosil is an aro matic coal tar product. Prontosil's full chemical formula is the disodium salt of 4-sulph-amido-phenyl-2-azo-7-acetylamino-1-hydroxynaphthalene 3.6-disulfonic acid. All doctors fear new drugs derived from coal tar. They may exhibit unexpected deadliness. In the case of Prontosil, since like dinitrophenol it affects the production of white blood cells, it comes under the medical rule of thumb: what ever stimulates may also destroy. And it may be that the new drug by which Dr. Tobey cured Franklin Roosevelt Jr.'s septic sore throat...

Author: /time Magazine | Title: Medicine: Prontosil | 12/28/1936 | See Source »

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