Word: acidated
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...same kind of help that the Soviet Union gives to Castro." The result was a flat turndown: Miro was told that the U.S. remains determined to oust Castro (presumably by economic strangulation), but that the U.S. will not permit its policies to be controlled by exile "war parties." In acid Spanish, Hurwitch told Miro that the exiles must fall into line or "no Cuban exile will obtain access to U.S. Govern ment officials again...
...model Dr. Hofmann selected ribonuclease, a much-studied natural enzyme that breaks down the ribonucleic acid found in all cells. With delicate skill, he split the ribonuclease into two parts, one containing 20 amino acids, the other containing 104. In this disjointed condition the enzyme has no effectiveness. It is like a machine tool with the motor separated from the cutting edge...
...Hofmann patiently built a copy of the smaller fragment. After he had stuck 13 of the acids together, he joined his synthetic segment to the 104-acid remainder of natural ribonuclease. The reconstituted enzyme proved to have 70% of the activity of the natural substance. Apparently the seven amino acids, Nos. 14 to 20, that had been left out are like the chip collector on a lathe-useful but not essential...
...Hofmann then synthesized an eleven-acid segment and joined it with the rest of the enzyme. This substance proved wholly inert. Apparently amino acids Nos. 12 and 13 that he had just eliminated are at the "active site" of the enzyme, like the cutting tool of a lathe...
...short for D-lysergic acid diethylamide), by far the most potent, is a chemical relative of the ergot drugs, synthesized in 1943 by Swiss Chemist Albert Hofmann. As Discoverer Hofmann found, and countless psychiatrists have since confirmed, a dose of LSD-25 can be so small as to be almost invisible and still destroy a man's mental equilibrium, at least temporarily. As little as four-millionths of an ounce is sometimes enough to throw an emotionally wobbly individual into a mental hospital. One victim, ill for months, was a psychologist who was trying out LSD himself...