Word: acidic
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...steamy July morning in New York City last summer, Allergan, maker of Botox, unveiled the latest weapon in its aesthetic arsenal, Juvéderm. The new wrinkle filler--made from hyaluronic acid, a naturally occurring sugar in the skin that helps it hold moisture--had just got the green light from the FDA for distribution in the U.S. Champagne corks popped and a curtain parted to reveal a glamorous and wrinkle-free blond, seen minutes before on a video with a face full of creases and frowns. "This is the new generation of dermal fillers," gushed Caroline Van Hove, director...
...name. There are some potential wrinkles in that plan, though. Botox, a facial-muscle relaxant that was used by some 3.5 million people last year, had the market to itself; Juvéderm has a competitor before it's even out of the box: Restylane, the current best-selling hyaluronic-acid filler, made by Medicis, a $344 million dermatological company based in Scottsdale, Ariz. And Medicis' Perlane, a more robust version of Restylane, is expected to get the FDA's thumbs-up any day now. Down the road, there's a possibly even bigger blow, Reloxin, a Botox-like alternative...
...better seconds after application. How? They use optical elements that reflect light (Definity by Olay), pink pigments that enhance skin tone (Clarins' Night Wear) and micro-size sponge-like pearls that fill in pores (Instant Smooth by Clarins). Boutique product Freeze 24/7's claim to fame: gamma amino butyric acid, a natural muscle relaxant that temporarily eases the appearance of fine lines...
Unsure of the structure of a favorite amino acid? No more sifting through pages of results or toggling back and forth among 10 different windows. Harvard affiliates can now access information on more than 20 million chemical compounds, 11 million reactions, and 500 million chemical facts with the click of a mouse, thanks to a search platform the University recently purchased from Elsevier MDL, a leading publisher of scientific information. The software, DiscoveryGate, also allows users to categorize their results and link them to primary sources. Users can look up structures of various compounds, toxicity, metabolic pathways, and suppliers...
...Mike (Rory Kulz ’08), a passerby stranded by fog and a van crash, who rapidly joins in the fray. The action starts at a believable pitch and rapidly spirals into exaggeration and caricature. For the most part, this works, as it is delivered with an acid wit and cynicism that meshes nicely with the characters’ disintegration, giving the play something of a train-wreck appeal of watching them dig themselves deeper and deeper into an emotional pit. All of the actors (save Steinemann, who maintains a glacial calm throughout) go off the deep end with...