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...University and the Merck Sharp & Dohme Research Laboratories at Rahway, N.J. Working independently from different starting points and along different routes, both of the research groups reached the same end point: synthesis of ribonuclease, an enzyme found in the pancreas (sweetbreads) of cattle that helps to break down ribonucleic acid...

Author: /time Magazine | Title: Biochemistry: Synthesis of an Enzyme | 1/24/1969 | See Source »

...They Did It. The Rockefeller researchers, Drs. Robert B. Merrifield and Bernd Gutte, began their experiment with a tiny bead of plastic, onto which they hooked a 124-link chain of amino acids. There are 20 different amino acids, and, because all proteins, including enzymes, are made of amino-acid chains, the acids have been recognized for many years as the "building blocks of life." The exact sequence and identity of successive acids in the ribonuclease chain were recently established, and the Rockefeller team's job was to link them, one at a time. The painstaking process involved...

Author: /time Magazine | Title: Biochemistry: Synthesis of an Enzyme | 1/24/1969 | See Source »

...Merck researchers, Drs. Robert G. Denkewalter and Ralph F. Hirschmann, went at it differently. They prepared groups of six to 17 amino acids in linked series. They then put these groups together to form the ultimate 124-link chain. Their product turned out to be the same as the Rockefeller synthetic enzyme; its identity was proved by the way in which it broke down ribonucleic acid...

Author: /time Magazine | Title: Biochemistry: Synthesis of an Enzyme | 1/24/1969 | See Source »

Rock musicians are the bastard offspring of Horatio Alger, just as the hip movement is the enfant naturel of the middle class. The success ethic, entrepreneurial impulse, and belligerent independence of the robber barons are stamped indelibly in their acid-mutated genes as surely as in Lyndon Johnson's. The musicians wanted to make it, but the only possible way seemed to be to deny that they wanted to make it. All the accoutrements of the hip life in rock were reminders that you were first and foremost a Beautiful Person, with loyalties not to entertainment but to other Beautiful...

Author: By John Leone, | Title: Fading in Rock Phantasmagoria: A Personal Autopsy of the Boston Sound | 1/22/1969 | See Source »

Reasoner's fans are also served occasional acid. Two weeks ago on radio, he devised a game called Homeowner, in which "one person, designated the homeowner, immediately would be declared the loser, and the rest of the game would be spent determining how much he would lose." When Reasoner called the phone company to complain about digit dialing, the response made him fume: "They've got that defense in depth, whereby the first three people you talk to know only one phrase each, like a chimp trained to press a lever for a banana-flavored pellet...

Author: /time Magazine | Title: Newscasting: Television: Jan. 10, 1969 | 1/10/1969 | See Source »

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