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...Tagamet] is to shore up the battlements before Zantac," says Susan Coleman, managing partner of NCI Consulting in Princeton, New Jersey. When Zantac 75 wins approval for over-the-counter sales in the U.S., she predicts, "World War III starts." She notes that while other over-the-counter acid blockers had been on the British market for a year before Zantac 75 appeared in January, it took only three months to overwhelm the competition. "Zantac on the market will be a significant competitor," says Robert Kniffin, vice president of Johnson & Johnson's external communications. "We shall see." (As if Zantac...

Author: /time Magazine | Title: FIRE IN THE BELLY, MONEY IN THE BANK | 11/6/1995 | See Source »

...share of the entire antacid market. "Pepcid had a window of opportunity, and it exploited it well in the marketplace," says Silvermine Consulting's Kelly. "That's an amazing accomplishment." Amazing, and expensive. J&J/Merck and SmithKline are each spending some $100 million in marketing campaigns for their new acid blockers...

Author: /time Magazine | Title: FIRE IN THE BELLY, MONEY IN THE BANK | 11/6/1995 | See Source »

...Pepcid's quick strike, Tagamet's ambitious counterattack and the row over advertising may look like mere skirmishes when Zantac 75 enters the fray. This acid blocker is the over-the-counter version of Zantac, the top-selling prescription drug in the world and the pride of Britain's Glaxo-Wellcome pharmaceutical stable. Prescribed for 240 million patients around the globe, Zantac last year generated $3.6 billion in sales, $2.1 billion in the U.S. And last month the over-the-counter Zantac 75 received a recommendation from an FDA advisory committee, virtually assuring its imminent approval for sale...

Author: /time Magazine | Title: FIRE IN THE BELLY, MONEY IN THE BANK | 11/6/1995 | See Source »

...antacid products. In touting Tagamet HB, for example, SmithKline has to avoid invidious comparisons with Tums, its antacid moneymaker, while J&J/Merck must tiptoe around any comparisons between Pepcid AC and its antacid, the much advertised Mylanta. Meanwhile, Switzerland's Ciba-Geigy has other worries. Though it has no acid blocker available that could bite into sales of Maalox, its bread-and-butter antacid, its competitors' new drugs almost certainly will...

Author: /time Magazine | Title: FIRE IN THE BELLY, MONEY IN THE BANK | 11/6/1995 | See Source »

Though hurt by the onslaught of acid blockers, the lower-priced and faster-acting antacids will almost certainly maintain a respectable market share. Tums, for example, costs less than 3¢ a tablet. That compares with more than 40¢ for a one-a-day Pepcid AC tablet or a Tagamet HB two-tablet dose, although both products currently offer substantial rebates. Still, booming sales of the new acid blockers seem to show that heartburn sufferers are not troubled by sticker shock. At a Duane Reade drugstore in Manhattan, Darlene Jackson, 35, picked up a box of Tagamet HB and noted...

Author: /time Magazine | Title: FIRE IN THE BELLY, MONEY IN THE BANK | 11/6/1995 | See Source »

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