Word: adhd
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Dates: during 2000-2009
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...Wendy Weber, a naturopathic physician at Bastyr, the group decided to study St. John's wort after the Food and Drug Administration approved atomoxetine - an agent that keeps nerve endings in the brain flooded with the neurotransmitter norepinephrine - for treating ADHD in children. They knew from previous studies that at least one of St. John's wort's active ingredients, hyperforin, has the same effect on brain neurons, and speculated, as have other proponents of alternative therapies, that the botanical might help to relieve symptoms of ADHD without a prescription. But among the 54 children between six and 17 years...
...popular herbal remedy for treating attention deficit hyperactivity disorder (ADHD) in children actually does little to improve symptoms of the disease, according to a new study. Researchers at Bastyr University in Washington state report in the Journal of the American Medical Association (JAMA) that St. John's wort, a commonly used botanical to treat depression, does not help children with ADHD to concentrate or curb hyperactivity any more than a rice-protein placebo over an eight-week period. It's the first such study to tackle the question of St. John's wort's effectiveness against ADHD in a randomized...
Weber notes, however, that hyperforin tends to oxidize and therefore lose potency in pill form. More recent formulations, she says, may retain this potency slightly longer, and therefore may have greater effects on ADHD symptoms - but only an additional study can establish whether that's the case...
...size well before middle age. It also begins to use the brain's fuel, glucose, less efficiently and loses about half the neurotransmitter dopamine it once had. The result of all this, says Amy Arnsten, a neurobiologist at Yale Medical School, is that as we get older, we get "ADHD, but it's attention-deficit hypoactivity--not hyperactivity...
...Yale, Arnsten has roused idling monkey and rat brains with a medication called guanfacine, which appears to amplify the circuits of the prefrontal cortex. The drug has been tested on children with ADHD as well as on people with traumatic brain injury, posttraumatic stress and schizophrenia, and in each case it seems to revitalize working memory...