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...cultural consciousness, as that Big Different Place. It?s a European city on the East Coast, tall instead of wide, with more foreigners than natives, more liberals than in the entire media conspiracy (which is also based here), and people who can spend their entire adult lives without ever owning or needing a car. No wonder it took a couple of jet-plane bombs and several thousand surprise deaths to get the folks outside of New York - they call themselves Americans - to sympathize with...
Rowling also had a hand in choosing most of the adult cast members. She specifically requested Coltrane. Others, like Richard Harris as Dumbledore, Maggie Smith as Professor McGonagall and Alan Rickman as Professor Snape came straight from a wish list of actors that Rowling provided the producers. She gave Rickman and Coltrane precious bits of information about their characters' futures. "There's an awful lot revealed about Hagrid in book five," says Coltrane, "and Jo thought it was important for me to know." Like what? "I could tell you," says Coltrane, "but then you'd have...
...former category includes dipping her hand in barrels of grain and cracking the fine crust of a crème brûlée with a teaspoon. Home-schooled by neurotic, hugging-averse parents, she grows up painfully shy and enclosed in her own fantasy world. Unfortunately, her adult life doesn’t seem much better. She works as a waitress in a quintessentially Parisian café, where the regulars comprise a dysfunctional family of their own. But one day she discovers a box of toys in her apartment and resolves to find its owner. This sets...
...passed in 1997, pediatricians had little information on whether drugs were safe or effective for their young patients, and often had to guess how to calibrate doses of even well known medicines. For drugmakers, testing drugs on kids wasn't profitable; the money was in the adult market. The law led to a flurry of studies (more than 400) and labeling changes that have been helpful for treating children, though at a huge cost: pediatric studies that often cost companies just a few million dollars often reap them rewards totaling hundreds of millions thanks to the extended monopolies...
...with revenues of $2.5 billion per year, most realized a fix was needed, and other brand-name drugmakers didn't like the notion of an exemption for BMS. The Senate approved a bill with a provision clarifying that generic drugmakers can sell their version of a drug in an adult form even if the brand- name maker has changed its label by adding new pediatric information. The House bill that passed in committee has similar language; a vote on the House floor could happen Tuesday. But generic drugmakers and other opponents of BMS' effort worry that a measure favoring...