Word: adults
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...wiry little man-child with a voice that sounded like his novocaine hadn't worn off yet. But children adored Pee-wee Herman (aka Paul Reubens), critics praised him and adults delighted in discovering double-entendres and inside jokes on his Saturday morning kids? TV show Pee-wee?s Playhouse, which ran from 1986 to 1991 on CBS. Pee-wee is back - this time for grown-ups - in all 45 original episodes, airing on Cartoon Network?s Adult Swim Monday thru Thursday nights at 11 p.m. TIME's Jeanne McDowell talked to Reubens about the return of the Playhouse...
...Playhouse on Adult Swim...
...point, the father records that his son would like to talk to an accuser face to face, "with an adult present." There's a notation that the father has called another parent, left a message, and hasn't received a return phone call. The pages of the notebook are filled with comments that seem to have been made during phone calls and conversations, and they reveal snapshots of trouble...
...hard to appreciate why. Mammalian cloning is an intricate process involving at least three animals, hundreds of eggs, hundreds of more mature cells and not a single sperm. The key challenge is to undo the development of an adult cell--which, like all cells, contains in its DNA the genetic blueprint of the entire organism--that has been programmed or "differentiated" to be one kind of cell (skin or bone or nerve) and no other kind. Somehow, scientists must trick this mature, fully developed cell into resetting its genetic clock so that it can begin life anew as an embryo...
...process by which that is achieved is called nuclear transfer. The first step is to remove the nucleus from an egg and replace it with the nucleus of an adult cell (in Dolly's case, a cell from a ewe's udder). The two components are electrically fused and chemically activated to trick the hybrid cell into dividing like an embryo. Not surprisingly, the process doesn't always go right. "I call it a lottery," says Wilmut. "Even if you use the same method as consistently as you can, you may get some clones with severe abnormalities and some that...