Word: aerosporin
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Dates: during 1940-1949
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Last week, after ten years and 1,000 experiments, stocky Scotsman George Brownlee, 37, thought he had something. His research team at Wellcome Physiological Laboratory, Beckenham, Kent, had produced a new antibiotic from bacteria (Bacillus aerosporus) found in soil from a market garden. The antibiotic is called aerosporin (pronounced a-ross-poe-rin). The researchers' tests and findings were reported with cautious excitement in Lancet...
...test tubes, aerosporin proved many times more effective than streptomycin, weight for weight, against typhoid, dysentery, cholera, the plague, other intestinal infections. In mice, it worked against the whooping cough organism (which defies other antibiotics), typhoid, possibly against enteric fever...
...also worked in its first test on human beings-ten children, one month to 2½ years old, suffering from whooping cough. All showed definite improvement in the first 48 hours. (Two of the children later died, but neither death was due either to whooping cough or to aerosporin...