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...study, which was conducted on mice, is part of a hot new area of research called epigenetics, which explores how experiences and environmental exposures affect genes. "This is a major step in understanding the development of cocaine addiction and a first step toward generating ideas for how we might use epigenetic regulation to modulate the development of addiction," says Peter Kalivas, professor of neuroscience at the Medical University of South Carolina, who was not associated with the study. (See the top 10 scientific discoveries...
Around the time he started collecting the data, Bygren had become fascinated with research showing that conditions in the womb could affect your health not only when you were a fetus but well into adulthood. In 1986, for example, the Lancet published the first of two groundbreaking papers showing that if a pregnant woman ate poorly, her child would be at significantly higher than average risk for cardiovascular disease as an adult. Bygren wondered whether that effect could start even before pregnancy: Could parents' experiences early in their lives somehow change the traits they passed to their offspring...
...devils will eventually need a vaccine, and there is hope that this research may help scientists develop one. The team compiled a catalog of devil genes that affect the tumor and may contribute to its growth; these could be useful targets for designing a future vaccine. The difficulty will be creating a treatment that attacks the tumor, but spares healthy cells. "The key in a vaccine is not to create immune action that would hurt the devils by attacking their Schwann cells," says Papenfuss. "Now we can look for specific markers on the tumor cells to attack." Tough as they...
...second study in the same journal, researchers at Iowa State University used computer modeling to figure out how the length of a runner's stride might change the force applied to his or her bones and thereby affect the risk of stress fractures. Researchers recruited 10 male participants, each of whom typically ran about three miles per day, and calculated their risk of experiencing a stress fracture - about 9% over 100 days. By observing the participants running at varying stride lengths and recording the amount of force their foot strikes exerted on the ground, researchers were able to estimate...
...Open Space Council on habitat conservation strategies in central California. The new research informs one of the key challenges conservationists face: having only limited funds to buy up land, and, thus, having to spend wisely. "What we bring," says Ackerly, "is the ability to think about how topography might affect those decisions...