Word: agammaglobulinemia
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...painstaking laboratory work wiih gutsy speculations, or "probes," much in ihe manner of a medical Marshall McLuhan. On one occasion, while treating a patient whose inability to resist infection coincided with the growth of a massive thymic tumor, Good began to speculate about the link between the thymus and agammaglobulinemia, a disease caused by a deficiency or lack of the major antibodies. He?together with others in his laboratories?conducted a series of experiments in which he removed the thymus from newborn rabbits. The results of the test?all of the animals failed to develop normal immune systems?...
...Martin Schulkind and Elia Ayoub of the College of Medicine of the University of Florida have used transfer factor to treat effectively chronic mucocutaneous candidiasis, a severe fungal infection of the skin and mucous membranes; others have used it successfully to treat agammaglobulinemia and Wiskott-Aldrich syndrome, a hereditary defect that leaves its victims unable to resist certain infections...
...another meeting in Atlantic City, the Association of American Physicians (dubbed, willy-nilly, "the Old Turks") heard about a new disease with a name like a Greek railway station: agammaglobulinemia. This is the condition which exists, said Dr. Charles A. Janeway of Harvard Medical School, when a patient lacks his natural share of gamma globulin, the immunity-carrying element in human blood. So far, all such patients have proved to be male...
...Colonel Ogden C. Bruton, is rare, fortunately, and is probably a byproduct of the antibiotic age. "Before the days of penicillin," said Dr. Janeway, "these patients must have succumbed to the extremely severe infections which either caused the condition or first brought it to light." Nobody knows yet whether agammaglobulinemia is present at birth or is picked up later in life. But its discovery may help to explain why some patients never seem to develop resistance against normally mild infections, and may die as a result...
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