Word: agee
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Dates: during 2000-2009
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...leading theory to explain this fortunate disconnect is the brain-reserve hypothesis, which suggests that people who have more cognitive ability and more neural tissue to start with - sharper minds, broadly - may be better able to withstand the ravages of age. "In some ways, you could think of it like a trained athlete who might be able to resist some atherosclerosis of the heart," explains Dr. Bradley Hyman, director of the Massachusetts Alzheimer's Disease Research Center and a professor of neurology at Harvard Medical School...
...finding adds to a collection of studies suggesting that the greater one's initial mental fitness - measured variously as higher educational achievement or high IQ, for example - the better it may be safeguarded in old age. "It's broadly consistent with the notion that if someone starts out with the ability, however their brain is organized, to have a greater set of skills in language and performing other complicated tasks, then maybe that brain is more resistant [later in life]," says Harvard's Hyman. (See the top 10 scientific discoveries...
...research, conducted as part of the National Institute of Aging Interventions Testing Program, took place at three separate test sites and involved nearly 2,000 genetically similar mice. Trials began when mice were about 600 days old - well into middle age, at a stage roughly equivalent to 60-year-old humans. (See the top 10 medical breakthroughs...
...been linked to hyperlipidemia, or high levels of triglycerides in the blood, which can lead to heart disease. It's unclear whether these problems would counteract any longevity benefit that rapamycin might provide in humans. Says Strong, "I think more immediately, people are starting to look at [rapamycin] for age-related diseases like Alzheimer's disease, Parkinson's disease or kidney disease." The drug has also recently entered clinical trials as a human cancer treatment, while another study published last year showed that it may reverse mental retardation caused by the genetic disease tuberous sclerosis in mice. (See TIME...
...convenient case study, we should note that the opting-out revolution is largely a myth. A study in the American Sociological Review in June 2008 found that fewer than 8% of professional women born since 1956 have left the workforce for a year or more during their prime childbearing age. Most working mothers, the Census Bureau reports, are back in the workforce within a year of having a child; better-educated women and those who can afford to drop out are actually less likely to. Rather than the pull of the playground, 86% of women in one survey cited...