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...flew to Houston, where he was given a briefing on a new agent called ibalizumab, an antibody that appeared able to block HIV's entry into healthy cells. In the 200 or so HIV-positive patients tested in the early trial, the compound was effective, but Tanox was worried about resistance. No matter how promising ARV drugs were, HIV inevitably found a way to evade them. So while the agent seemed to reduce the burden of virus in the blood up to 90% in patients with full-blown AIDS, no one knew how long the viral standoff would last...

Author: /time Magazine | Title: David Ho: The Man Who Could Beat AIDS | 1/25/2010 | See Source »

DEFNE BAYRAK, wife of the double agent who killed seven CIA operatives and a Jordanian intelligence officer in a Dec. 30 suicide bombing on an American base in Afghanistan...

Author: /time Magazine | Title: Verbatim | 1/25/2010 | See Source »

Espionage boomed during the 20th century, as World War II and the Cold War made invisible ink and encrypted messages more than just fodder for thrillers. Austro-Hungarian agent Dusko Popov, the reported inspiration for Ian Fleming's James Bond, gallivanted around Europe feeding false intelligence to the Nazis and sleeping with countless women. (His fondness for ménages à trois earned him the code name Tricycle.) British spymaster Kim Philby spent 30 years rising nearly to the top of MI6, only to be unmasked as a double agent in 1963--having sent decades of secrets to the Soviets...

Author: /time Magazine | Title: Brief History: Double Agents | 1/25/2010 | See Source »

...Ophelia mad scene. As Diane, a young Englishwoman in Southern California, she's in hysterics when Mitchum first sees her (they exchange hard slaps); later she toys portentously with chess pieces and glowers at us out of a fetal position. By the end Diane has been the agent of two gruesome car crashes and four deaths. "I don't pretend to know what goes on behind that pretty little face of yours," Mitchum tells her, "and I don't want to." Yet for the length of the movie he denies his better instincts to get closer to this petite praying...

Author: /time Magazine | Title: Jean Simmons: Portrait of a Complicated Lady | 1/24/2010 | See Source »

Where is it coming from? According to the U.S. Drug Enforcement Agency, levamisole has become increasingly popular as a "cut," or diluting agent, in cocaine and possibly some heroin. It is now found in 70% of all cocaine seized in the U.S., up from 30% in 2008. Unlike most cuts - usually inert or relatively harmless substances like the B vitamin inositol, which are added by lower-level dealers looking to stretch supplies - levamisole appears to be added to cocaine from the outset, in the countries of origin. The substance has been found in various concentrations in cocaine analyzed in countries...

Author: /time Magazine | Title: A Common Cut in Cocaine May Prove Deadly | 1/20/2010 | See Source »

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