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...answer. The University of Toronto scientist had spent his career trying to sift out the misshapen clumps of proteins thought to cause neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) that hid in a sandbox of normal proteins. In 2002 he finally succeeded, using a chemical agent to alter normal proteins but not so-called aggregated misfolded ones, leaving the clumps easier to detect. It would become the formula for a diagnostic kit usable by blood banks everywhere...

Author: /time Magazine | Title: GEORGE ADAMS: Find the Bad Protein; Then, Fix It | 11/14/2007 | See Source »

These great institutions have seen new arrivals suddenly realize that being a member of such a world-renowned pressure-cooker may not be so great after all. Every year New York seems to see another fine free agent acquisition’s career burn out, and Harvard faces the arrival of many a freshman for whom endless open houses and Annenberg ice cream are cold comfort in the face of a newfound anonymity amongst fellow lifelong standouts. Both departing Yankees great Alex Rodriguez and, by his own admission, UC President Ryan A. Petersen ’08 nearly cracked under...

Author: By Max J Kornblith | Title: No Place for Losers? | 11/14/2007 | See Source »

...free agent signing period gets going this week, the union is sufficiently frightened that the fix could be in again that it is gearing up an investigation. "Any such activity with respect to free agents is clearly improper," says Donald Fehr, the executive director of the Major League Baseball Player's Association. "We expect to look into the situation, and are prepared to take appropriate action to respond to any collusive behavior, and to make sure the rights of free agent players under the Basic [collective bargaining] Agreement are fully protected...

Author: /time Magazine | Title: A-Rod's Salary: Watching for Collusion | 11/13/2007 | See Source »

...stark. The arbitrator found, for example, that the American League president and two owners - Jerry Reinsdorf, who still controls the Chicago White Sox, and one Bud Selig, then owner of the Milwaukee Brewers - called the president of the Philadelphia Phillies to dissuade him from signing Lance Parrish, a free agent catcher from the Detroit Tigers...

Author: /time Magazine | Title: A-Rod's Salary: Watching for Collusion | 11/13/2007 | See Source »

...suggestion that such a discussion violates the Basic Agreement is absurd," says Rob Manfred, baseball's lead labor lawyer. Still, the union thinks the meeting was suspect. Several press reports have also suggested that Commissioner Bud Selig - angry about both the scope of A-Rod's free agent demands and the timing of the opt-out from his New York Yankee contract (during the waning moments of this year's World Series, thus overshadowing the sport's signature event) - could be working the back rooms to keep A-Rod from scoring another pay raise. Manfred calls such allegations of tampering...

Author: /time Magazine | Title: A-Rod's Salary: Watching for Collusion | 11/13/2007 | See Source »

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