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...shuffling gait or uncontrollable tremors in the hand. But the neurodegenerative process behind the condition can also trigger anxiety or other psychological disorders and--as scientists learned this year--so can the treatment. A Mayo Clinic study found that in rare cases, treatment with a so-called dopamine agonist led 11 patients to develop compulsive-gambling habits (two reported losses over $60,000). Four had never gambled before, but all the patients stopped their wagering within months after treatment was discontinued. The effect was apparently greatest with the drug pramipexole, which investigators theorize indirectly triggered the "reward system...

Author: /time Magazine | Title: A-Z Guide to the Year in Medicine | 11/27/2005 | See Source »

Plenty of war blogs are also posted by stateside armchair pundits. Sean-Paul Kelley, who runs The Agonist (at agonist.org) says traffic to his site has increased more than tenfold, to over 60,000 visitors a day, since the war began. From his home in San Antonio, Texas, the self-employed asset manager posts 10 to 20 news updates a day, culled from dozens of websites and media reports from such far-flung outlets as the Sydney (Australia) Morning Herald and the Army Times. Each posting gets about 100 replies, which are also posted online...

Author: /time Magazine | Title: Tech: Best Of The War Blogs | 4/7/2003 | See Source »

Like methadone, the compound that activates D1 appears to be what is known as a partial agonist. Because such medications stimulate some of the same brain pathways as drugs of abuse, they are often addictive in their own right, though less so. And while treating heroin addicts with methadone may seem like a cop-out to people who have never struggled with a drug habit, clinicians say they desperately need more such agents to tide addicts--particularly cocaine addicts--over the first few months of treatment, when the danger of relapse is highest...

Author: /time Magazine | Title: ADDICTED: WHY DO PEOPLE GET HOOKED? | 5/5/1997 | See Source »

...drug is an attractive alternative to beta-agonist, the traditional asthma treatment which is taken as an inhalant. Rather than simply relaxing muscles which have already contracted, zileuton inhibits activity of the molecule which initially causes the muscle to contract...

Author: By Virginia A. Triant, | Title: New Drug for Asthma Patients Discovered by Med School Team | 2/22/1994 | See Source »

...another demonstration," he said. Harry Ring, the editor of the Militant, then got up and said he opposed a demonstration against Mayor Stokes. He said the black people of Cleveland were under an illusion, and their "level of consciousness" was such that they would not march agonist Mayor Stokes...

Author: By Story STEVEN W. bussard, | Title: The Cleveland Conference: What Did It All Mean? | 6/29/1970 | See Source »

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