Search Details

Word: agouti (lookup in dictionary) (lookup stats)
Dates: all
Sort By: most recent first (reverse)


Usage:

...organism was proposed in the 1970s, yet it wasn't until 2003 that anyone experimented with DNA methylation quite as dramatically as Duke University oncologist Randy Jirtle and one of his postdoctoral students, Robert Waterland, did. That year, they conducted an elegant experiment on mice with a uniquely regulated agouti gene - a gene that gives mice yellow coats and a propensity for obesity and diabetes when expressed continuously. Jirtle's team fed one group of pregnant agouti mice a diet rich in B vitamins (folic acid and vitamin B12). Another group of genetically identical pregnant agouti mice got no such...

Author: /time Magazine | Title: Why Your DNA Isn't Your Destiny | 1/6/2010 | See Source »

...vitamins acted as methyl donors: they caused methyl groups to attach more frequently to the agouti gene in utero, thereby altering its expression. And so without altering the genomic structure of mouse DNA - simply by furnishing B vitamins - Jirtle and Waterland got agouti mothers to produce healthy brown pups that were of normal weight and not prone to diabetes...

Author: /time Magazine | Title: Why Your DNA Isn't Your Destiny | 1/6/2010 | See Source »

...winter. The Siamese came to the ancient royal family of Siam from somewhere else. No one knows where. This most neurotic, intelligent and wonderfully expressive feline made its U.S. debut with Mrs. Rutherford B. Hayes in the 1870s. The spirited, assertive Somali is a long-haired Abyssinian with agouti coloring-each hair is individually striped with brown or black. With its habit of pacing back and forth, it often resembles a miniature mountain lion...

Author: /time Magazine | Title: Living: Top Cats: Breeds Apart | 12/7/1981 | See Source »

Broome eight years to ferret out the guinea pigs' secret. These animals, and a few closely related species such as the agouti, have in their blood the enzyme L-asparaginase, so called because it effects a chemical breakdown of the amino acid L-asparagine.*Many of the body's cells need asparagine as a source of nourishment, and normal cells manufacture it within themselves. But some types of cancer cells, which also need it, cannot make it. So they steal it from healthy cells...

Author: /time Magazine | Title: Cancer: Secret from the Guinea Pigs | 4/14/1967 | See Source »

...show, however, had one crisis. From among 75 black, blue, red, chocolate, cinnamon, silver, champagne, fawn, and agouti-colored rats & mice, and from 150 white, blue-cream, smoke, red tabby, and tortoise-shell cats, a Siamese named Marvella and a fancy rat named Minnie were chosen to appear together in an amicable picture. When Cat Marvella reached out a tentative paw of friendship. Rat Minnie flew into a huff, sank her sharp teeth into the paw. Marvella whimpered, withdrew her foot...

Author: /time Magazine | Title: Miscellany, Dec. 6, 1937 | 12/6/1937 | See Source »

| 1 | 2 | Next