Word: ahf
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Fast Freeze. Since all normal blood contains AHF when fresh, transfusion is an obvious answer. But the volume needed may amount to several pints a day, more than the patient's system can stand if the treatment has to be repeated often-as it usually does. And all transfusions carry the risk of hepatitis infection or severe allergic reactions. It was not until 1965 that a Stanford University physiologist, Judith Graham Pool, developed a technique of freezing, thawing and centrifuging fresh plasma to concentrate the AHF. (The rest of the plasma could still be broken down into a dozen...
...hemophiliac usually had to go into a hospital to get it. The material could be extracted from only the freshest of plasma. Even the short delay between collection by a mobile blood unit and delivery at a blood center was long enough to destroy or damage the AHF...
...blood-collecting unit, the nation's first auxiliary van equipped with a freeze-centrifuge apparatus. And recently Dr. Kenneth M. Brinkhous, a blood scientist at the University of North Carolina, collaborated with Dr. Edward Shanbrom of the Hyland (Los Angeles) division of Baxter Laboratories to perfect a new AHF six or seven times as strong as Dr. Pool's cryoprecipitate. The new preparation, 30 to 50 times as active as plasma, has just gone on the market...
...greater concentration makes it possible to give the normally required amount of AHF by hypodermic injection into a vein-and in only five minutes. Moreover, this can be done in the doctor's office or an out-patient clinic. One of the first and most grateful beneficiaries of the new treatment system is David M. Raatz, a California attorney who lives in Monrovia and practices in San Marino. At 26, Raatz has had gallons of plasma and concentrates to stanch the bleeding that recurs most commonly in his ankles, knees and elbows. He never used to know when...
...Yourself Cost is still a problem. For a patient like Raatz, there is no predicting how often he will need AHF, or just how much. His expenses have run as high as $150 in a week, but for him and most other patients they average about that per month over the long run. Prices are expected to come down when the supply increases. The demand is there: U.S. hemophiliacs need the AHF from 1,000,000 pints of blood each year...