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What the hemophiliac's blood lacks, because of a genetic defect transmitted from mother to son, is a clotting protein known as antihemophilic factor (AHF) or globulin (AHG), also called Factor VIII. Because of this deficiency, the hemophilia victim lives in constant danger of severe bleeding from the most minor wound, such as a finger cut or a tooth extraction. Even with no external injury, he may bleed internally after a bump or a stumble. This is especially likely to happen inside his joints, causing arthritis with progressive deformity and disability...

Author: /time Magazine | Title: Hematology: Help for Hemophiliacs | 8/16/1968 | See Source »

Saving the Bleeders. In another series of experiments on animals, a Boston City Hospital team sponsored by the Harvard Medical School reported the possibility of spleen transplantation to save the lives of hemophilia victims. Hemophiliacs suffer from the lack of a blood-clotting substance called AHF. As a result, an otherwise manageable cut can become a source of quick death. At present, when a severe onset of hemorrhaging occurs, hemophilia victims can be saved from bleeding to death by injections of AHF extracted and concentrated from a healthy person's blood. But the process is costly, and the relief...

Author: /time Magazine | Title: Transplants: Making Progress | 10/20/1967 | See Source »

...known that the spleen is somehow involved in the production of AHF, but just how is not yet clear. Experimenting with pigs, the Boston City Hospital surgeons found that a normal spleen begins to produce more AHF when perfused with the blood of a hemophiliac. To one of the surgeons, Dr. John C. Norman, this suggests the possibility of transplanting a normal spleen into a hemophiliac, so that his abnormal blood might stimulate the new spleen into plentiful production of AHF...

Author: /time Magazine | Title: Transplants: Making Progress | 10/20/1967 | See Source »

During these years Monro taught General Education Ahf. He has been a proponent of extention of tutorials, freshman seminars, and a more flexible Gen Ed program. Since he became Dean in 1958, Monro has placed himself in the position as a spokesman for student ideas in Faculty meetings. "During the last few years," Dean Ford said Wednesday, "Monro's reports to the Faculty on student attitudes has provided an essential interpretation of what is the best and most responsible student opinion...

Author: By Boisfeuillet JONES Jr., SPECIAL TO THE CRIMSON | Title: Monro to Resign July 1 as Dean of College; Glimp Will Be Recommended as Successor | 3/10/1967 | See Source »

...courses, bearing titles such as "Exposition and Autobiography," are being offered this year along with a lower group course entitled "English Composition" in place of the old General Education Ahf...

Author: By Lee H. Simowitz, | Title: New Gen Ed Program Runs Smoothly | 9/29/1966 | See Source »

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