Word: alongism
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Dates: during 2000-2009
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...second paper in Nature, published by the same team at CHOP along with scientists at numerous other institutions, looked at a specific kind of genetic change: deletions and duplications of genes. While there are many such changes associated with autism, most are very rare. This paper, however, found an intriguing pattern among two genes already linked to autism and nine newly identified targets. Most play a role in two key systems in the brain. One is the same brain-wiring system - neural cell adhesion - implicated in the first paper. The second is a set of housekeeping proteins - the ubiquitin system...
...with autism are beginning to make some kind of sense. "We are starting to get convergence around genes that affect how synapses and connections in the brain are made and maintained ... particularly in the frontal lobe" says Geraldine Dawson, chief science officer for Autism Speaks, an advocacy group that, along with the National Institutes of Health, funds the AGRE database. The hope, says Dawson, a co-author of the two Nature papers, is that researchers could ultimately develop drugs that affect the biochemical pathways associated with these genes. Drugs that are precisely targeted in this way are already being tested...
...Kroin laid out a series of plans to address what he said were the three main goals distilled from previous CWP discussions: increasing the Charles River’s accessibility to Allston, connecting currently disparate neighborhoods with green pathways and street networks, and aggregating commercial and cultural activity along Western Ave. at several focal points...
...With a bona fide ace and an experienced offense intact, Harvard rolled through the preseason with its best record in years, picking up two tournament wins along...
...Harvard, as the pair of senior skipper Jon Garrity and sophomore crew Grace Charles won the division by 20 points over Boston College. The duo finished among the top half of the 18-team field in all but one of their 18 races on the weekend, earning five victories along...