Word: alongism
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...second paper in Nature, published by the same team at CHOP along with scientists at numerous other institutions, looked at a specific kind of genetic change: deletions and duplications of genes. While there are many such changes associated with autism, most are very rare. This paper, however, found an intriguing pattern among two genes already linked to autism and nine newly identified targets. Most play a role in two key systems in the brain. One is the same brain-wiring system - neural cell adhesion - implicated in the first paper. The second is a set of housekeeping proteins - the ubiquitin system...
...with autism are beginning to make some kind of sense. "We are starting to get convergence around genes that affect how synapses and connections in the brain are made and maintained ... particularly in the frontal lobe" says Geraldine Dawson, chief science officer for Autism Speaks, an advocacy group that, along with the National Institutes of Health, funds the AGRE database. The hope, says Dawson, a co-author of the two Nature papers, is that researchers could ultimately develop drugs that affect the biochemical pathways associated with these genes. Drugs that are precisely targeted in this way are already being tested...
...Kroin laid out a series of plans to address what he said were the three main goals distilled from previous CWP discussions: increasing the Charles River’s accessibility to Allston, connecting currently disparate neighborhoods with green pathways and street networks, and aggregating commercial and cultural activity along Western Ave. at several focal points...
...Hungry for local food? Check out the Phantom Gourmet Wine and Food Phest for a massive sampling of food from Boston Area restaurants. The event features 30 of the anonymous TV reviewer’s favorite foods along with 30 wines. Nom nom nom. Tickets are available at wine.phantomgourmet.com. 21+. Saturday, May 2, 2 p.m. – 8 p.m., Bayside Expo and Conference Center, $30 online 2. From the Venetian Lagoon to the Bay State: Go see the MFA’s current special exhibition! “Titian, Tintoretto, Veronese: Rivals in Renaissance Venice” gathers...
...Culture,” gave students a crash course in Israeli food and culinary traditions. The history of Jewish and Israeli food is largely intertwined with Israel’s turbulent history, but according to Ben-Yehoyada, “what we eat doesn’t travel along the same lines as our politics.” The region’s culinary identity began to take shape in the decades following Israel’s formation—in 1948, the United Kingdom terminated the British Mandate of Palestine, which had placed the region under British rule...