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The technique could be applicable, for example, to other disorders that affect the cardiovascular or nervous system such as amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), as scientists could potentially grow heart or nerve cells.
The newly created cells made insulin in diabetic mice, though they were not cured. But if the experiment's approach proves viable, it might lead to treatments like growing new heart cells after a heart attack or nerve cells to treat disorders like ALS, formerly Lou Gehrig's disease.
The answers to those questions, says Eggan, may come in a matter of "months, not years." It's still unclear whether the new iPS nerve cells can live up to the gold standard of cells created from human embryonic stem cells, but Eggan, Henderson and their colleagues are confident that...
"We now have in the culture dish cells which have the same genetic makeup as do the ALS patients, and they are the very cells that are affected by the disease." said Columbia professor Christopher Henderson, referring to Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative often called Lou Gehrig's Disease...
In addition, the stem cells are specific to only a certain type of the disease, which afflicts less than five percent of sufferers, Eggan said. But the study authors said research on this less-common variant could have broader applications, if, as they hope, the disease mechanism is similar for...