Word: alvac
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...vaccine, called RV144, combined two older vaccines that had each proved unsuccessful in previous tests: ALVAC, from Sanofi Pasteur, the vaccine division of French drugmaker Sanofi-Aventis; and AIDSVAX, originally developed by VaxGen Inc. and now held by the nonprofit Global Solutions for Infectious Diseases...
...vaccine was administered in two stages. First the ALVAC vaccine, which uses a Frankenstein virus of canarypox and HIV, was used as a primer dose, then AIDSVAX was administered as a "booster" to improve the body's immune response to the first shot. Half of the trial's participants received the combination vaccine, while the other half received a placebo. In the final analysis, 74 of the 8,198 placebo recipients became infected with HIV, compared with 51 of 8,197 participants who received the vaccine regimen...
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