Word: amethopterin
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There were as many dissents as there were theories, and since so few drugs cure viral infections, the very fact that potent anti-cancer drugs such as amethopterin (Methotrexate) and cyclophosphamide (Cytoxan) have cured massive cases of Burkitt's supermalignant tumor might seem to argue against a viral cause. But doctors now believe that what the drugs do is cure or relieve a viral-induced cancer, after the virus itself may have vanished. Thus they may give the body an opportunity to develop its own mechanisms to fight the cancer...
...Boston Children's Hospital and the Children's Cancer Research Foundation. Knowing that leukemic cells are avid for the vitamin folic acid, he began in 1947 to treat child victims of acute leukemia with analogues of folic acid. Lederle Laboratories sent Dr. Farber two, aminopterin and amethopterin. which soon brought about improvement in most of the children. But after weeks or months, their disease became resistant...
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