Word: amino
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Dates: during 1960-1969
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...said his work indicates that it of three bases--the code-- acid that determine amino if the four kinds of bases in RNA are represented by the A, B, C, and D, ABC may result of one amino acid, ACB . The nucleic acid chain which these two amino acids...
...must be arranged in proper three starting from a on the chain, Crick said, to the amino acids. In other words, base A is removed from the ABC-ACB, the chain now begins and neither amino acid will be But in some cases, Crick stated, of a base at one point on may compensate for the a base at another...
...defective chain BCA-CB. B is inserted between BC, ACB in the new chair BBC-ACB. second amino acid would be as before, although base A moved from the original chain The expected mutation--that acid would be formed-- "suppressed," Crick said...
Certain groups of three bases may not determine an amino acid. If in the original chain ABC was such a "nonsense group," the change to BBC in the new chain will not affect the formation of the protein, Crick pointed out. Thus restoring the second group ACB restores the protein...
Actually this description is oversimplified. Crick said, for he feels that more than one group of three bases is necessary to determine an amino acid. Thus while there are only 20 amino acids, there may be more than 50 "sense" triplet groups of bases, groups which influence amino-acid formation...