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Word: anafranil (lookup in dictionary) (lookup stats)
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...breakthrough in OCD treatment came about in the late 1980s, when researchers discovered that a particular antidepressant, clomipramine hydrochloride (brand name: Anafranil), relieved obsessions and compulsions as no others did. The presumed secret of its success was its ability to inhibit the reabsorption of serotonin in the brain. A few years later, the advent of the ssri family made it even more obvious that obsessive-compulsive disorder was at least in part a serotonin problem. Some 75% to 80% of ocd patients today get substantial relief--sometimes complete remission--from one or another member of the SSRIS...

Author: /time Magazine | Title: TARGETING THE BRAIN | 9/18/1996 | See Source »

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