Word: anemia
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Dates: during 1950-1959
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Danger on the Side. Primaquine has one peculiarity: it is much safer for white patients than others; Negroes and many Asiatics may develop a form of anemia after relatively small doses. Also, it has to be given in several doses, so it is not the ideal drug for such a vast area of relapsing malaria as India...
...Mountain spotted fever, brucellosis (undulant fever), typhus and some kinds of pneumonia, it had been given to about 8,000,000 patients since it was first marketed in 1949. Then it was found (TIME, July 14) that some patients who had been getting the drug had died of aplastic anemia (in which the bone marrow is unable to do its normal job of making red and white blood cells...
After a quick and thorough check by topnotch authorities, the Food & Drug Administration gave its verdict last week. Chloromycetin was connected with the deaths of at least 72 aplastic anemia victims. However, there are "serious and sometimes fatal diseases in which its use is necessary," the FDA decided; therefore, doctors may still use it. But the manufacturers, Parke, Davis & Co., must warn doctors on the leaflet packed with every bottle that studies of the patient's blood are essential if Chloromycetin is given for a long time. Further. "Chloromycetin should not be used indiscriminately or for minor infections...
...whole field of vitamins, Merck's greatest triumph, by far, is its most recent. Its chemists extracted the elusive anti-anemia factor from liver in pure form: the ruby-colored crystals of vitamin B12, essential to growth and the most powerful medicinal substance known in nature. One thirty-millionth of an ounce a day is enough for a healthy man's blood-making factory; one three-millionth checks pernicious anemia...
Though Bob can dash 100 meters in 0:10.7 (Olympic record: 0:10.3), a childhood case of anemia still leaves him short of the endurance required to run the metric mile. It is just about his only athletic shortcoming. He is a one-man track team, capable of winning the majority of U.S. college track meets singlehanded. His best official discus throw, 173 ft. 4 in., is 2 in. better than the Olympic record...