Word: anemia
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...study of 25 children published in the New England Journal of Medicine last week, the unusual treatment may work better than a bone-marrow transplant in treating the childhood cancer. Placental blood might even be used someday to treat other blood and immune-system disorders--from sickle-cell anemia to AIDS...
Combination therapy still has its problems. The medications can interact with one another to cause side effects. Even by themselves they can cause severe diarrhea, abdominal cramps or anemia. Some of the drugs have to be taken on an empty stomach, others on a full stomach, so it can be hard to stick to a regimen. Yet if patients skip even a single dose of any one drug, the HIV could press this small advantage to mutate into a strain that resists all current medicines. Nor is everyone so sure that a cure is in sight. "Virologists have started using...
CONNIE SESSOMS, 41; CHARLOTTE, N.C.; Trucking Business A regular blood donor since 1972, Sessoms was the first to participate in a local pilot program for children with sickle-cell anemia, where he was paired with a specific patient with similar characteristics. There is a medical reason for the one-to-one matchup: transfusions from the same donor may help children build antibodies, lengthening the time between crises. Says Sessoms: "I would do whatever it takes to make another's life a little easier...
Like every medical revolution before it, the field of gene therapy began with the vision of a brighter future. Researchers promised to cure such hereditary disorders as cystic fibrosis, muscular dystrophy and sickle-cell anemia, not with conventional medicine but with the magic of genetic engineering, supplanting defective genes with their normal counterparts. Patients dreamed of a life free of the diseases they had inherited. Venture capitalists dreamed of untold riches and backed the leading researchers in the field with millions of dollars of seed money...
HOSPITALIZED. MICKEY MANTLE, 63, Baseball Hall of Famer, this time for anemia caused by chemotherapy; in Dallas. Barely two months after undergoing a liver transplant, Mantle revealed he had begun treatment for cancer that had spread from his diseased liver to his lung (had the cancer been detected earlier, the donor liver would have gone to someone else...