Word: anemia
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This arcane process of "auto-allergy" may be an important factor in many cases of anemia, in rheumatoid arthritis and myasthenia gravis, and in kidney and thyroid diseases. Last week, at the second of two Manhattan conferences on what many doctors prefer to call "autoimmune disease," researchers added impressive evidence on two recent additions to the catalogue of such ills: ulcerative colitis and pernicious anemia...
...body has safeguards so it can recognize 'self as opposed to 'not-self,' and it will not damage 'self materials. Occasionally these safeguards break down." Dr. Dameshek detected such a breakdown in 1937 when he was treating three patients for severe hemolytic ("blood-destroying") anemia. They needed transfusions, but in the blood of each patient the doctor found a factor that made cross-matching difficult. He discovered that both the donors' blood cells and the patients' own were being destroyed by an antibody mechanism. Dr. Dameshek deduced that the patients had developed antibodies against...
Missing Messenger. Pernicious anemia has remained a mysterious disease despite the finding that it can be controlled (though not cured), first by liver extracts and now by vitamin B12. Cornell University's Dr. Graham Jeffries began by studying the inflammation of the stomach lining that precedes pernicious anemia. This robs the patient of a biochemical messenger which normally conveys B12 through the digestive system to the body. In patients' blood, Dr. Jeffries reported, he has found antibody of a type that attacks the stomach-lining cells...
...immediate cause of death was anemia: the Reporter simply ran out of money. Never able to pay its own way, the tabloid managed to avert death only by desperate expedients. At the end, more than half the Reporter's staff was still unsalaried and subsisting entirely on meager strike benefits: up to $79 a week. Even its offset press was leased for a token $10 a year from the benevolent International Typographical Union...
...Yourselfers. But the method has drawbacks and dangers. The WAVE developed gout* and anemia. It was the gout, and not hunger, that made her break her fast. Poe, the 550-pounder, also developed gout, and had a dangerous drop in blood pressure when he stood up. Four other patients showed the same drop in blood pressure. Only five men came through with no serious side effects, and none of these had lost more than...