Word: anemia
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Toxic reactions from the drugs are frequent-a survey of sulfas taken internally shows that some toxic reaction occurred in 29.8% of sulfapyridine cases, 11.8% of sulfathiazole and 7.7% of sulfadiazine. Most of these reactions are not dangerous, merely a nuisance (e.g., nausea, vomiting, dizziness, mild anemia, lack of appetite, tingling sensation), and do not interrupt treatment. But some rare reactions may prove fatal unless caught early. Even the less toxic sulfa derivatives can cause trouble: three cases at Johns Hopkins Hospital suffered not only kidney damage but brain injury from sulfathiazole; two majors in the Army Medical Corps last...
...Unlike sulfa drugs, penicillin has not yet shown any harmful effects. A patient's appetite often increases; his anemia may improve...
...Warren Cooksey, technical supervisor of Detroit's blood bank, thought the red blood cells should be saved if possible-they are the material needed in a large proportion of hospital transfusions (e.g., anemia), are ordinarily given to patients in whole blood purchased from professional donors at $25 a pint. Dr. Cooksey found that, mixed with a simple salt solution, red cells will keep in good condition for a little over a week, provided processing takes place within an hour of bloodletting. At his suggestion, the blood bank will soon send Detroit hospitals 800 pints of red blood cells...
...George Hoyt Whipple, professor of pathology at the University of Rochester, George Richards Minot, professor of medicine at Harvard, William Parry Murphy, practicing physician in Boston and associate at Harvard-a trio who shared (1934) the prize in physiology and medicine for their discovery of liver therapy for anemia...
...Said Dr. Snapper: "The parasitic disease which places its mark all over internal medicine in North China is kala-azar....It has to be considered in nearly every patient." This hideous malady, caused by tiny protozoa (Leishmania), produces an enormous spleen, anemia, and ulcers around the mouth, robs the body of its white blood cells, kills 95% of its victims who are not treated. Antimony is a specific for the disease, but of course few of its victims ever see a doctor until the disease is far advanced. Kala-azar is primarily an affliction of dogs, is passed to human...