Word: angina
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Dates: during 1980-1989
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...findings, researchers found that the bigger the drop in cholesterol, the lower the incidence of both fatal and nonfatal heart attacks. When the cholesterol level was reduced by 25%, the risk of heart disease was cut by 50%. The group on medication also had 20% fewer episodes of angina and 21% fewer coronary-bypass operations to restore the free flow of blood to the heart...
...institute's study does not challenge these applications of surgery. Instead, it focuses on whether or not bypass operations extend the life of patients with less severe heart disease. Some of those selected for the study were suffering from mild to moderate angina, the viselike chest pains that signal a decreased supply of blood to the heart; others had a history of one or more heart attacks but did not have recurrent chest pains. The 780 participants, all under age 65, were randomly treated either with bypass surgery or with drugs, such as nitroglycerin and diuretics, that ease pain...
...Eugene Braunwald, chief of medicine at both Beth Israel Hospital and Brigham and Women's Hospital in Boston. To avoid a second operation, Braunwald and a growing number of his colleagues believe that the first bypass should be put off as long as possible by controlling symptoms like angina with drugs. "What we're doing with drugs is buying time," he explains. The institute's study has shown that this can be done safely...
...drugs that help reduce the burden on the heart, made it possible for certain patients to postpone or avoid surgery altogether. Patients may also benefit from the introduction in the U.S. two years ago of substances called calcium channel blockers, which can reduce blood pressure, relieve some types of angina and help the heart work more efficiently...
...potentially dangerous clotting of blood, earlier tests showed it to be of limited help to patients who have already had a heart attack. The new data, however, clearly demonstrate that small doses are very effective in preventing heart attacks in people who have had the warning signs of unstable angina...