Word: angina
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Attempts to reach Sakharov's home in Moscow by telephone were unsuccessful. Sakharov had suffered from angina, but during a visit to the United States in December 1988, doctors at Massachusetts General Hospital determined he did not need heart surgery or a pacemaker after cardiovascular tests...
...SmithKline Beckman, developer of the anti-ulcer drug Tagamet, last week approved a merger with London's Beecham Group, which has built strong European markets. One week earlier Dow Chemical agreed to merge its Merrell Dow Pharmaceuticals subsidiary with Marion Laboratories, whose chief prescription drug is Cardizem, an angina treatment. In the afterglow of the Time-Warner marriage and other such deals, companies in many industries may gain greater confidence to embark on friendly combinations...
Ischemia occurs when coronary arteries partly clogged with fatty deposits of plaque suddenly contract in spasms or are blocked by a clot, depriving the heart muscle of blood and thus oxygen. While painful or "noisy" ischemia (angina) often results from physical stress, like climbing stairs, even slight exertions, like balancing a checkbook, can trigger silent ischemia. During these episodes, which typically last a few minutes but can go on for ten hours, large portions of heart muscle can be damaged. Yet in more than 75% of all cases, for still unknown reasons, the victim feels no pain...
...most of them with the same condition as Lewis', known to doctors as familial hypercholesterolemia, or FH. In Moscow, eminent Soviet Cardiologist Yevgeni Chazov is treating another ten FH patients, working closely with the Rogosin Institute in an unusual Soviet-American collaboration. Both overseas groups report that their patients' angina has decreased and that they perform better on stress tests...
...rare and extreme version of FH. Yuko, 11, of Osaka, Japan, has been treated for nine years by Dr. Akira Yamamoto of the National Cardiovascular Center, earlier with a crude version of cholesterol filtering and more recently with a process similar to that used at Rogosin. Racked by angina at age two, she can now climb a flight of stairs without stopping. What is even more impressive to scientists is that X-ray studies show that her disease has actually regressed. "Atherosclerosis of her renal artery has completely disappeared," exults Yamamoto, and blockage around the aortic valve "is almost gone...