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...Roche Holding AG, the Swiss holding company for Tamiflu manufacturer Hoffman-La Roche. Tamiflu sales dropped off sharply in the second half of 2007, Roche announced this week. But the main reason wasn't drug-resistance; it was simply a saturated market. As countries meet their targets for an anti-flu-pandemic Tamiflu stockpile, global demand for the drug is tapering off. For now, at least, those national stockpiles still offer an advantage: To date, the H5N1 bird flu shows only limited resistance to the drug...

Author: /time Magazine | Title: Drug-Resistant Flu Virus on the Rise | 1/31/2008 | See Source »

John McCain is too pro-immigration for these latter-day Perotistas. And Mitt Romney is too hedge fund. If either of them won the Republican nomination, a souped-up Perot could win over downscale Republicans who like Mike Huckabee's anti-corporate populism. And he might pick up a few John Edwards supporters as well?white male union types who think Hillary Clinton and Barack Obama are too pro-immigration...

Author: /time Magazine | Title: The Bloomberg Delusion | 1/31/2008 | See Source »

...April 17, 2006, cover story, "Dropout Nation," helped spark a national discussion of one of America's most pressing educational problems: the more than 1 million students who give up on high school each year. As a result of that story, we became part of the anti-dropout coalition led by Colin Powell's nonprofit, America's Promise Alliance, which is launching 100 summits in 50 states to tackle this problem...

Author: /time Magazine | Title: Democracy Reborn | 1/31/2008 | See Source »

That walkout was the culmination of a decade in which stand-up became the voice of the counterculture generation. Like George Carlin, Richard Pryor and other pioneers of those years, the new stand-up comics were not just anti-Establishment rabble rousers; they were intimate, populist artists who got their power by convincing us that they were ordinary folks, with the same gripes and anxieties as everyone else. They joked about furnishing their tiny apartments and riding the subways and trying to get girls. The strike against the Comedy Store, the leading comedy club in Los Angeles, reinforced their real...

Author: /time Magazine | Title: The First Comedy Strike | 1/31/2008 | See Source »

...Giuliani collapse wasn't totally unexpected?a twice-divorced, pro-choice, anti-gun New Yorker was a tough sell in a Republican primary?the cause certainly was. Who would have expected the mayor who declared war on criminals, squeegee men, graffiti artists, jaywalkers and even purveyors of "incivility"?in other words, New Yorkers?to shy away from a fight...

Author: /time Magazine | Title: Mr. Sunshine | 1/31/2008 | See Source »

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