Word: antiarrhythmia
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Dates: during 1990-1999
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DCRI has been designed to find vital but frequently obscure medical information. Califf's favorite illustration involves an antiarrhythmia drug that had passed clinical trials, was approved by the FDA and was being given to thousands of patients before it was discovered that the drug was killing some patients. "You'd think that doctors would notice people falling over dead," says Califf. "But these things happen over years." These problems not only happen over time; they also often happen in patients who had other medical conditions that might have killed them. And they happen amid a large pool of people...
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