Word: antibioticized
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Mycobacterium tuberculosis. Plasmodium falciparum. Staphylococcus aureus. Streptococcus pneumoniae. Enterococcus faecium. Neisseria gonorrhoeae. The list of microbial scourges that have developed immunity to one or more of the drugs used to treat them is growing ever longer, and in a number of cases physicians are running out of options. In U.S...
Modern medicine has engaged disease-causing microbes in an escalating arms race, so that as soon as drug developers launch a new weapon--an antibiotic, for example--their microbial foes respond by shoring up their own defenses. Sometimes bacteria and parasites undergo random mutations that spontaneously confer resistance. More frequently...
The current attack against resistant strains is multipronged. Some microbiologists are trying to re-engineer the older generation of miracle drugs to get around the mechanisms of resistance. Tetracycline, which kills bacteria by disabling a cellular structure known as the ribosome, is the target of one such effort. Bacteria become...
Nature is not the only lode that drug developers are mining. Linezolid, the novel antibiotic just approved by the FDA, is totally synthetic, and that is a great advantage, believes Pharmacia Corp.'s Dr. Gary Tarpley, who led the team effort that produced the drug. "Because this compound has never...
As you might expect, diarrhea is the traveler's No. 1 health complaint. Most people are usually back to normal after a couple of days. You should consult a doctor, however, even while still abroad, if you develop a fever or your stools become bloody. Many physicians prescribe an antibiotic...