Word: antigenically
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...Clifton Bennett, announced a sure, swift, new syphilis test. A sore trial for pathologists, the speedy test, invented in 1935 by Dr. George Franklin Laughlen of Toronto, Ont., was fussed over for four years before it could be made practical for general use. Using the new technique and "Laughlen antigen" in 150 syphilis blood samples, Professor Kirk called all the shots, made no false diagnoses...
...three drops of blood are taken from a finger or an ear lobe and centrifuged to remove all red blood cells. Then the clear serum is mixed with several drops of the antigen, a witches' brew of benzoin (a resin from Java or Sumatra), cholesterol (alcohol which occurs in bile), scarlet red (a dye), plain salt water, and alcoholic beefheart extract. If syphilis antibodies are present in the blood, coarse particles develop in the colorless fluid, and clumps of red granules appear around the edges of the mixture. Since the reaction is clearly visible to the naked...
They are a disgrace." At the same time enthusiasm marked the 40th convention of the Society of American Bacteriologists in San Francisco. For 38-year-old Dr. Walther Frederick Goebel of the Rockefeller Institute Hospital announced that he had produced artificially a successful pneumonia antigen. (An antigen is a substance which stimulates the organism to produce antibodies ; a serum is a blood constituent in which antibodies have already been produced.) The Goebel antigen is a combination of egg white and an acid obtained by complicated treatment of cellulose products (such as sawdust, straw or wood fibres) with water...
Large-scale production of the antigen, agreed the enthusiastic bacteriologists, would be cheap, simple and eliminate the necessity of using rabbits...