Word: antitoxins
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...Percheron horse who has had a mild case of diphtheria for almost nine years wore a garland of flowers around his neck for a party last week. He was 14-year-old Doc Dobbin, oldest diphtheria antitoxin horse in the laboratories of E. R. Squibb & Sons at New Brunswick, N. J. Because Doc Dobbin has produced antitoxin enough to treat 30,000 children, Dr. John F. Anderson, Squibb vice president, gave a birthday party on the anniversary of Doc Dobbin's ninth year of service. One hundred school children from Highland Park, N. J. attended. The birthday table...
...taken from a person who has recently recovered from infantile paralysis. Convalescent serum has been scarce and difficult to get. Drs. Marcus Neustaedter, neurologist, and E. J. Banzhaff, serologist, have hit upon a procedure of producing the proper serum in a horse, the handy and prolific source of diphtheria antitoxin. This serum immunizes monkeys against the disease. It has even cured them when given quickly after they were infected. In the U. S. and Europe some five dozen children, some of them in the early paralytic stages, have received treatment. All recovered. Their recoveries warranted last week's report...
...ingenuity last week in diphtheria prevention work. At the suggestion of its Diphtheria Prevention Commission (Morgan Partner Thomas William Lament, president), Health Commissioner Shirley W. Wynne borrowed a half-dozen trucks from the street cleaning department, cleaned them, placarded them with warnings against diphtheria, and advice to use toxin-antitoxins. Aboard each car he loaded a doctor, two nurses and a refrigerator full of toxin-antitoxin. Then these "healthmobiles" rolled forth among the city's millions like itinerant waffle carts. Spectacular, convenient, they "sold" the idea of preparing in July for winter's diphtheria, administered great numbers...
Later Dr. Theobald Smith, of the Rockefeller Institute, found that if a little diphtheria toxin were added to antitoxin the mixture would immunize animals against the disease. At once Dr. William Hallock Park, director of New York City's health department laboratories, and his associate, the late Dr. Abraham Zingher, began to immunize children with the toxin-antitoxin mixture. That mixture is what the "healthmobiles" were administering last week. Three to six months are necessary before immunity is established...
...Chicago physicians proved that doctors have found little use for vaccines to cure disease, the open-minded American Medical Association hastened, last fortnight, to publish the facts. Vaccines immunize against specific infection. For several years doctors, further, have believed that diligent experiment would show them a vaccine, serum, or antitoxin * to cure any particular disease. Many an agent was tried, and many a disappointment ensued. In Chicago Dr. Ludvig Hektoen and Ernest E. Irons wondered at the extent to which U. S. physicians are now using vaccines to cure disease, as against preventing disease. Accordingly they sent questionnaires to specialists...