Word: ap
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Dates: during 1990-1999
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...work. This is where the problem of remyelination comes in. Studies of multiple sclerosis patients have proved useful; MS is an autoimmune disorder in which immune cells strip the spinal-cord nerves of their myelin. Decades ago, MS researchers began testing a derivative of coal tar, 4-aminopyridine (4-AP), to help MS patients gain as much use of their existing nerves as possible. The benefit of 4-AP in paralysis studies came when research with animals showed that a lack of myelin was significant in loss of muscle control. Paralyzed animals given intravenous 4-AP were not necessarily able...
Since 1990, about 100 paralyzed patients have been given 4-AP in clinical trials, and about one-third of them have regained some function. Keith Hayes, a neuroscientist at the University of Western Ontario in London, Canada, who has been involved in the trials, says, "We have seen improvements in sensation and motor function, reduced spasticity and reduced pain, and improvement in bowel, bladder and sexual functions." MS researchers may come up with yet another useful therapy for spinal-cord injuries. At the Mayo Clinic in Rochester, Minnesota, Dr. Moses Rodriguez is testing the use of antibodies as catalysts...
...DIEGO (AP)--Offering himself as a "bridge to a time of tranquility," Bob Dole accepted the GOP presidential nomination last night vowing to restore heartland values of faith and trust to a White House he called captive to elitists "who never sacrificed, never suffered...
...DIEGO (AP)--Colin L. Powell stepped into a starring role yesterday night as Republicans opened their national convention by celebrating Bob Dole as a tested, trustworthy leader who will lower taxes and bring compassionate conservatism to the White House...
...Press that it was possible that Nickles may have been contacted as a prospective running mate merely as a courtesy. Dole has said repeatedly in the past that his own 35 years in Congress would make it difficult to fill the ticket with a House or Senate member, the AP reported. Dole is expected to take great care in choosing a vice president, and not only because he would be the oldest U.S. president if elected. Other names that have emerged as potential veeps: former South Carolina Governor Carroll Campbell and five current Republican Governors, Tom Ridge of Pennsylvania...