Word: apo
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Dates: during 1990-1999
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...followers call him Apo, Kurdish for uncle. His enemies call him a terrorist and a "baby killer." But last week, Abdullah Ocalan, proud leader of the violent Kurdistan Workers' Party (P.K.K.), was just the cowed captive of the country he had fought for more than 14 years. As he sat strapped into the seat of a jet en route to Turkey, his face dripped with sweat and his eyes blinked nervously while he told his captors how much he "loved" Turkey and how eager he was to "render services" to them. Then he requested medicine for his heartburn...
...carry a defective version of a gene involved in making beta amyloid, it is well established, have high rates of Alzheimer's, which lends weight to the beta amyloid theory. But many more people, observes Duke University neurologist Dr. Allen Roses, carry an Alzheimer's-susceptibility gene known as Apo-E4, which produces a protein that appears to affect tau. Individuals who carry two copies of this gene, Roses has shown, have an elevated risk of developing Alzheimer's before age 70. And if they suffer a stroke, warns another report published in last week's J.A.M.A., they are more...
...possibility of early diagnosis arises from advanced brain-mapping technology and new insights into the genetics of Alzheimer's. In recent years, researchers have learned that the disease is linked to the presence of a gene called Apo-E4. But the gene does not always trigger the illness; people with one copy of the gene have perhaps a 50% chance of getting Alzheimer's, and for those with two copies the likelihood rises to about 90% by age 80. In no cases can geneticists reliably predict at what age the disease will start...
...test. Led by Dr. Gary Small, a UCLA psychiatrist, the study focused on a small group of middle-aged volunteers, all of whom had relatives with Alzheimer's and who complained of mild memory problems themselves. First the researchers drew blood samples to test for the presence of the Apo-E4 gene. Then they used a PET scanner (positron emission tomography) to record each patient's pattern of brain activity. After a computer sifted through the data, a striking correlation emerged. A group of 12 individuals who had inherited Apo-E4 showed diminished activity, particularly in the parietal region...
...young Americans wait for their presents in the desert. They come addressed to Operation Desert Shield, APO New York, 09848-0006. They are parcels of home shipped into a zone that is nearly as alien and inhospitable as space -- temperatures unnatural, planet sand-colored to the horizon, days blinding, nights full of stars. Home, built around the cave and fire pit, belongs to a more Teutonic, cold-weather scheme of things...