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...viral bobble head's feet, where the virus fuses to the cell it infects. These regions mutate less rapidly, and in fact, in the recent study in mice, published in the current issue of Nature Structural & Molecular Biology, they did not mutate at all. "If we use this approach judiciously, we should be able to keep this pocket conserved and not develop drug resistance to it," says Dr. Wayne Marasco of the Dana Farber Cancer Institute, a co-author of the paper. "The exciting part is that this is really a therapy that can be used for prophylaxis and treatment...

Author: /time Magazine | Title: Getting Closer to a Flu Supervaccine | 2/23/2009 | See Source »

...binding site of the cells themselves, blocking the virus at the receiving end too. One more advantage of this viral weak spot: it's the same on the vast majority of influenza strains circulating each year, including the ones responsible for the bird flu, H5N1. That makes this antibody approach potentially useful not only against seasonal flu but against pandemic strains as well. (See pictures of the bird...

Author: /time Magazine | Title: Getting Closer to a Flu Supervaccine | 2/23/2009 | See Source »

...Princeton way. For 20 years, that hasn’t worked. But for the Crimson, there’s always next year. WHO’S HOUS’? The one thing that has worked for the Crimson at Jadwin Gym in recent history is not an offensive approach, but one standout scorer: senior guard Drew Housman. For four years, he has led the Crimson at the helm, trying to pull his team to that ever-elusive victory at Princeton. Two years ago, he came incredibly close, willing his team to two overtimes and the brink of victory, only...

Author: By Walter E. Howell, CRIMSON STAFF WRITER | Title: NOTEBOOK: Drought at Princeton Continues for Crimson | 2/23/2009 | See Source »

...were launching a retail concept in today's economy, how would you approach it? I think, as a culture, we are over-stored. All store chains would be healthier if they were smaller. If I were to act on a new retail concept today, I would ask, 'how do I marry the idea of a physical asset with an online world?" So rather than saying 'I'm going to have Victoria's Secret and then have victoriassecret.com, can I stand back and conceive of an online business which has a physical manifestation that drives...

Author: /time Magazine | Title: How Consumers Shop Differently Today | 2/22/2009 | See Source »

...Yang signaled that China was willing to work with the U.S. on trade, human rights and reducing carbon emissions. And Clinton's emphasis on discussion and consultation has thus far resonated with China. "I think in principal China wants the Obama administration to adopt a cooperative approach to dealings, rather than a confrontational approach," says Yan Xuetong, director of the Institute of International Studies at Tsinghua University in Beijing. "They would like to begin talking about things on an equal footing...

Author: /time Magazine | Title: Clinton Takes a Softer Approach to China | 2/21/2009 | See Source »

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