Word: approaches
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...development. To be sure, when they do hit the jackpot, the payoff can be enormous: Roche's pharmaceutical division alone raked in more than $30 billion in sales last year. Its total sales reached $43 billion, generating profits of $10.5 billion. Nonetheless, the days of this trial-and-error approach may soon be over. All of Big Pharma is feeling pressure--from Wall Street, regulators and customers--to take a smarter path to discovery for that next blockbuster drug. And who wins vs. who is left behind is still very much...
...demand for cancer drugs, for one, will grow exponentially with this treatment approach. But more important, Roche can now use biomarkers to determine much earlier in the R&D process whether a drug will pan out. Down the pipeline, diagnostics identify which patients most benefit from a therapy, giving clinical trials tailored to that subset a better chance of succeeding. Moreover, any patient for whom the drug wouldn't work or whom the drug could harm can be excluded...
Pierpaolo Barbieri ’09 is a history concentrator in Eliot House. His column, “Foreign Intelligence” will approach international politics from a historical and economic perspective, bringing the rest of the world to the ivory tower on alternate Thursdays...
...Other platforms take a less serious approach. George X. Huang ’12 is making promises to build an adult-sized playground on campus. “This is very ambitious,” his Facebook site acknowledges, “but a preliminary goal of 10-15 swing sets would be fantastic, even in winter.” In addition, he proposes a “bunny breeding” program to increase the presence of the furry animals on campus. The Facebook group for Agnes Z. Dardas ’12 says that...
...hours before the House of Representatives smacked down the financial-bailout package, I watched John McCain - eyes flashing, jaw clenched, oozing sarcasm and disdain - on the attack in Ohio: "Senator Obama took a very different approach to the crisis our country faced. At first he didn't want to get involved. Then he was 'monitoring the situation.' That's not leadership; that's watching from the sidelines." And I thought of Karl Rove. Back in 2003, at the height of Howard Dean mania, Rove was skeptical about Dean's staying power as a candidate: "When was the last time Americans...