Word: arsenicated
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Dates: during 1920-1929
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Tryparsamide, a new arsenic compound developed at the Rockefeller Institute, for the treatment of African sleeping sickness, has been used with considerable success as a remedy for paresis at the Wisconsin Psychiatric Hospital, Madison, by Dr. Arthur S. Loevenhart, professor of pharmacology at the University of Wisconsin, and Dr. W. F. Lorenz, chief of the Hospital...
Practically all efforts to attack paresis hitherto have been frustrated because antisyphilitic drugs, usually mercury or arsenic compounds, cannot pass through the choroid plexus, a sort of fine filter at the base of the brain. The germs which reach the higher centers are free to develop and soon do permanent damage to the brain tissue...