Word: aspirin
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...truth is that no medication--not even a nonprescription drug like aspirin--is 100% safe. Whether you realize it or not, whenever you take a drug, you are weighing the potential benefits against the possibility that the medicine can hurt you. So it pays to find out as much as you can about any drugs--including herbal remedies--you are taking...
When the COX-2 inhibitors hit the market in 1999, doctors and patients alike expected a lot from the little painkillers. The old standbys--which include aspirin and ibuprofen (Advil)--can tear up the lining of the stomach and cause serious bleeding disorders. These side effects occur when a protective enzyme called cyclo-oxygenase 1, or COX-1, is suppressed. Because the COX-2 inhibitors don't affect COX-1, it was expected that they would have fewer side effects...
...only one asking questions. Patients with a variety of concerns have been flooding physicians' phone lines with inquiries about Celebrex and Vioxx, two examples of a heavily advertised new class of analgesics called COX-2 inhibitors that are supposed to be easier on the stomach than aspirin. Some folks wanted to discontinue their medication; others just needed to hear that the potential cardiac threat was only theoretical and not proved...
...meta-analysis, published in last week's Journal of the American Medical Association, showed that those who took COX-2 inhibitors suffered slightly more heart attacks than those who took older, aspirin-like drugs. The authors considered several explanations. Since the older drugs help prevent heart disease, the JAMA study might only be picking up the absence of a protective effect in the COX-2 inhibitors. Or the new painkillers might actually promote the creation of blood clots. Or both processes might be at work. The point, Topol says, is that "the cardiovascular effects of the [COX-2 inhibitors...
...tell my friends I loved them, and then minutes later start a fight. I was failing out of school, drinking every day, ditching classes. I stole a lot from my parents, I couldn't hold down jobs. I was big into either cutting myself or drinking a lot with aspirin, or taking a lot of poisons. I managed to hide those suicide attempts from my parents. When I'd wake up in the morning, I couldn't look at myself in the mirror...