Word: aspirin
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...decision stands, it might open the door for holders of similar patents to target other drug makers with infringement claims. Signaling of the NF-kB molecule—the process at issue in Ariad’s dispute—is used by more than 200 compounds, including aspirin, according to Science magazine. Perhaps anticipating a future lawsuit, biotech company Amgen last week filed a pre-emptive motion asking a Delaware court to find Ariad’s patent invalid. The Thousand Oaks, Calif.-based firm also sought a ruling that its drug products do not infringe on the patent...
...Pharmacia in 2000. A win for Ariad and the co-plaintiffs, Rai said, would favor patent holders making claims on other drugs that use the same signaling pathways to a particular molecule. According to Science magazine, a recent paper said more than 200 compounds use NF-kB signaling, aspirin among them. “NF-kB ought to be available to anybody who wants to make a drug against it, and the terms should not be unreasonable,” Roger Brent, president of the nonprofit Molecular Sciences Institute, told Science. “It’s potentially quite...
Even if moderate drinking does confer health benefits, which it probably does, they are rather modest--certainly not stronger than the effect of small daily doses of aspirin on heart health. Indeed, according to Dr. Ira Goldberg, a preventive-medicine expert at the Columbia University College of Physicians and Surgeons in New York City, the effect may be more in line with the apparent cardioprotective benefit of eating a modest portion of nuts each day. Nuts, of course, aren't as sexy as alcohol...
...recent study by researchers from Harvard-affiliated Brigham and Women’s Hospital (BWH) has revealed significant gender differences in the effect of aspirin on men and women. Aspirin is recommended to people who have had or are undergoing a heart attack, according to Julie E. Buring, principal investigator of the study. The study, which will be published in the print edition of the New England Journal of Medicine later this month, found that aspirin can reduce the risk of stroke in women, but has little or no effect on the risk of heart attack. The opposite is found...
...food or non-alcoholic beverages, especially water. Also, skip drinking soda—carbonation can speed up intoxication and increase headaches. Time is the only true way to cure a hangover. Cold showers, exercise, and food will not speed up your body’s metabolism of alcohol. Aspirin or ibuprofen can sometimes be taken to prevent the headache pain. These drugs can cause some gastrointestinal discomfort, especially for those with sensitive stomachs. Harvey wants to stress that you must never take Tylenol or other acetaminophen while or after drinking, as it can react dangerously with the chemicals in your...