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...every once in awhile, the virus shifts its genetic structure so much that our immune systems offer no protection whatsoever. (This usually happens when a flu virus found in animals - like the avian flu still circulating in Asia - swaps genes with other viruses in a process called reassortment, and jumps to human beings.) A flu pandemic occurs when a new flu virus emerges for which humans have little or no immunity and then spreads easily from person to person around the world. In the 20th century we had two mild flu pandemics, in 1968 and 1957, and the severe "Spanish...

Author: /time Magazine | Title: Swine Flu: 5 Things You Need to Know About the Outbreak | 4/27/2009 | See Source »

...responsibility of declaring when a new flu pandemic is underway, and to simplify the process, the U.N. body has established six pandemic phases. Thanks to H5N1 avian flu, which has killed 257 people since 2003 but doesn't spread very well from one human to another, we're currently at phase 3. If the WHO upgraded that status to phase 4, which is marked by a new virus that begins to pass easily enough from person to person that we can detect community-sized outbreaks, such a move would effectively mean that we've got a pandemic on our hands...

Author: /time Magazine | Title: Swine Flu: 5 Things You Need to Know About the Outbreak | 4/27/2009 | See Source »

...H1N1 swine flu virus has already been identified as a new virus, with genes from human and avian flus as well as the swine variety. And since it is apparently causing large-scale outbreaks in Mexico, along with separate confirmed cases in the U.S. and Canada and suspected cases in other countries, it would seem that we've already met the criteria for phase 4. But though an emergency committee met on April 25 to evaluate the situation, the WHO hasn't made the pandemic declaration yet. Keiji Fukuda, the WHO's interim assistant director-general for health, security...

Author: /time Magazine | Title: Swine Flu: 5 Things You Need to Know About the Outbreak | 4/27/2009 | See Source »

...some ways, the world is better prepared for a flu pandemic today than it has ever been. Thanks to concerns over H5N1 avian flu, the WHO, the U.S. and countries around the world have stockpiled millions of doses of antivirals that can help fight swine flu as well as other strains of influenza. The U.S. has a detailed pandemic preparation plan that was drafted under former President George W. Bush. Many other countries have similar plans. SARS and bird flu have given international health officials useful practice runs for dealing with a real pandemic. We can identify new viruses faster...

Author: /time Magazine | Title: Swine Flu: 5 Things You Need to Know About the Outbreak | 4/27/2009 | See Source »

...After some initial missteps that allowed SARS to spread at an almost uncontrollable rate, Hong Kong was eventually heralded for its accomplishments in helping to rid the world of SARS and, a few years later, for its quick response to multiple avian flu scares. "I always think back to during the bird flu - some wild bird drops out of the sky and is found in Hong Kong. It finishes up in a lab, being dissected," says WHO's Cordingley. "Anywhere else it would be chucked in the garbage." (See pictures of change in Hong Kong...

Author: /time Magazine | Title: The Lessons from SARS | 4/27/2009 | See Source »

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