Word: azt
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Dates: during 1980-1989
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Congress last year created a $30 million emergency fund for AIDS patients who were unable to afford the high cost (about $8,000 a year) of AZT, the only FDA-approved drug known to prolong their lives. It did so on the unusual condition that the measure's sponsors would not try to renew the funding. For the 6,000 beneficiaries so far, a new crisis is at hand: although various states still have some of this money left, the federal program will end on Sept. 30 and a new grant is doubtful...
...began testing CD4 in AIDS patients. ! The arrival of CD4, which had been previously tested in mice and monkeys, marks the beginning of a promising new era in drug development. Scientists have traditionally stumbled onto treatments by testing existing substances for their therapeutic effects, as was the case with AZT, the only AIDS drug approved for widespread use by the Food and Drug Administration. But recent advances in the field of molecular biology have given researchers a clearer understanding of the most minute workings of the cell. This has enabled them to engineer structures that can disrupt the cycle...
...promise, no one expects that CD4 will cure AIDS. Yet the drug is a potentially important new weapon in a growing arsenal of treatments. Researchers are learning how to use AZT more effectively to interrupt the virus' life cycle inside a cell. Probably the best hope for a successful AIDS treatment lies in a combination of these and other drugs...
...have the disease nine years ago. He has recovered from pneumonia without the aid of medication five times. After a bout last year with two serious infections, he was put on interferon, which is supposed to boost the immune system but may cause pain. Now he is on AZT. "You have to have a cause to live for," declares Chandruss, who devotes much of his time to caring for other AIDS sufferers. He lives at a novitiate of the Alexian Brothers, a Roman Catholic order that runs an ambulatory-care center for AIDS patients. Despite his obvious energy, he admits...
...Yorker Marberger, the price of that faith is pain, resulting mainly from the experimental drugs he takes, that is so excruciating he must take a "pain cocktail" every four hours. Thus far he has tried interferon, aerosol pentamidine, which is used to treat deadly Pneumocystis carinii pneumonia, and AZT. He has also received dideoxycytidine, an antiviral medication. The treatment left him with tearing facial pains. Last week he was back in the hospital after a bout...