Word: azt
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...Doctors have been prescribing the AIDS drug AZT for pregnant women who test HIV positive. New findings confirm AZT can cut by two-thirds a mother's risk of transmitting HIV to her child--even if blood levels of the virus are extremely...
...prospect of salvation for people with AIDS seems closer than ever before. Since last November, almost 15 years after the first reported AIDS cases, the U.S. Food and Drug Administration has approved five new drugs that when taken in various combinations with the old standby, azt, have given new life to thousands of desperately ill people. This past summer, researchers isolated a gene that appears to protect some people from HIV infection--even after repeated exposure--and could lead to new genetic therapies against AIDS. Experiments being conducted this fall may tell doctors whether they can hit the virus hard...
Researchers had noticed that AZT kept HIV from being transmitted to the fetus in pregnant women. They tried to make the therapy more effective by working on pregnant monkeys, but PETA put a stop to their plans...
Then the FDA approved a new medication called saquinavir. One of the so-called protease inhibitors, it attacks the virus at a previously untargeted step in its reproductive process. Several similar drugs have since followed. The agency also approved a medication called 3TC. Although it works much like AZT, the two act as a chemical tag team: after HIV becomes resistant to AZT, it is still vulnerable to attack by 3TC. If it then develops resistance to 3TC, it suddenly loses the ability to fend off AZT. Multiple-drug therapy had finally become possible...
...latest promising treatments have been developed without animal research? Absolutely not, say AIDS researchers. Among other things, such studies help doctors determine what constitutes a safe dose of a drug before trying it out on people. The studies can also help physicians fine-tune treatments. After doctors determined that AZT could block the transmission of HIV to the fetus in some pregnant women, researchers wondered if they could make the therapy more effective. They decided to start by studying how a similar virus is transmitted from pregnant monkeys to their offspring. But animal-rights activists halted that experiment, saying...