Word: azt
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Kanki said cultural barriers in underdevelopedcountries lead to unequal access for women to AZT,currently a leading treatment for HIV-infectedpatients...
...only other anti-HIV drugs approved in the U.S. -- DDI and DDC -- are variations on the AZT theme. Researchers have begun examining other types, however. One variety targets the gene that codes for another enzyme, protease, that is crucial to the manufacturing of viral proteins. The research looks promising, but a breakthrough is not expected anytime soon...
...AIDS HAVE FORCED the U.S. Food and Drug Administration to further streamline drug-approval procedures. Last week a panel of experts recommended that the government agency give its conditional blessing to dideoxycytidine, or DDC. Although preliminary studies indicate that this antiviral medication may not work as well as AZT which still ranks as the premier AIDS treatment, the combination of drugs seems to rejuvenate some of the immune cells that are normally destroyed during the course of the disease...
Groopman has researched drugs such as AZT, which treats the HIV infection; GM-CSF, which helps restore patients' immune systems; and the recently-approved DDI, which appears to help control the HIV infection...
Developed by Bristol-Myers Squibb, DDI resembles AZT in that it interferes with replication of the AIDS virus. Whether it will extend the life of patients remains unknown, but it has been shown to boost levels of disease- fighting T cells. Last week's approval, granted with unusual speed, will enable doctors to prescribe the drug to those who cannot tolerate AZT -- about half of AIDS patients...