Word: barks
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...division in some fashion. Cyclophosphamide, the compound that finally banished Dustin Fagan's cancer, belongs to a broad class of drugs that damage the DNA molecule by plastering it with sticky cross-links, thus triggering the suicide sequence. By contrast, the taxoids--including taxol, the compound isolated from the bark of the yew tree that was approved by the Food and Drug Administration as a weapon against ovarian cancer in 1992--cause the same suicidal result by deactivating a molecular machine that, just before cell division, separates the DNA in each chromosome into two separate strands. Still other drugs known...
...this will matter only if Net surfers are still using Netscape software when that day arrives. And while Netscape has a dominant market share these days, the company has been seeing a little more of Microsoft's shadow than Bark likes. "We have enormous appreciation, admiration and fear [of Microsoft]," he says. "But like I tell people: I love my brothers, but I don't let them eat my supper...
...awake, I'm working." But plenty of others have tried to outwork Microsoft, and Gates has beaten them all. Barksdale's approach, at the very least, could someday lead to a kinder and gentler Valley culture. Whether Netscape's bottom line can hack that remains to be seen, but Bark believes his company deserves a little breathing room. "It's not a total win-lose game," he says. "I don't think anybody is going to have the dominant position in a network-centric world like they had in a desktop-centric world. I just cannot believe that." He pauses...
...biggest problems we have is that it's so hard to show results," says Frank Sanchez Jr., who runs delinquency-prevention programs for the Boys & Girls Clubs of America. The child who doesn't get into trouble is the dog that doesn't bark. "We don't have a lot of studies to build a broad, knowledgeable base," agrees Kristin Moore, executive director of the research firm Child Trends Inc., because most of the efforts to help kids are "too late, too shallow, too brief and too cheap...
...speed bike cooked up out of spare parts. He wouldn't make small talk, often wouldn't even finish a sentence. The dogs figured him out long before the feds did. "All the dogs hated him," recalled Rick Christian, 48, a longtime local. "They'd chase him, bark at him, growl at him when he walked or rode his bike. I had to call them off him before...