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...classes to New York City in 2006 and now offers them in Los Angeles, San Francisco and Chicago. "It's one of our most popular classes," says Donna Cyrus, Crunch's senior VP of programming. Legworks, which offers the workshop I went to in Manhattan, has a growing fan base. The Los Angeles high-end shoe store Il Primo Passo holds high-heel-walking classes, taught by a drag queen, of course, on a monthly basis...
...general, Colorado and its high-tech, adventure-travel economic base are somewhat insulated from the kinds of industrial shifts that have walloped Rust Belt states. But the exodus of wealth from Arapahoe has made it more vulnerable to economic downturn. In 2006 the county's foreclosure rate was five times the national average, and it's still one of the highest in the state. "When a flattening economy like we're experiencing now comes along," says Ritter, "they're going to be hit harder...
...Roche, the rush to innovate is palpable across the world's fifth largest pharmaceutical firm. In core research areas, scientists are mining new sources for inspiration, be it China or genetic engineering. At the same time, Roche's bosses, from their base in Basel, continue to lead the pack in acquiring expertise, a talent recently seen in the company's bid to control biotech superstar Genentech. Together, the two strategies form the nucleus of how Roche plans to deliver best-in-class products--faster, more cheaply and more reliably--to market. "The days of an attrition-based pipeline are over...
...good medicine for the accountants too. Roche can better forecast its future customer base, allowing it to do much more precise cost-benefit analysis ahead of time. "A drug can take 12 years or longer to develop from start to finish," says Steve Sembler, who oversees Roche's U.S. commercial operations. "Diagnostics give us a much longer-term perspective and take a lot of the guesswork out of the process...
...every other week’ way.” Flanzraich also accredits the success of the show to both the consistency of its production—about 15 episodes per year—and the quality of the product, both factors that have helped create a broad, reliable viewing base...